Archive for the ‘Pain’ category

Advantages and Disadvantages of Cocaine

May 9th, 2012
Dr.Badruddin Khan asked:




Aside from a few extremely limited medical uses, cocaine has no other purpose except to give a person an intense feeling of pleasure known as a “high.” While this may not seem like such a bad thing, the great number of physical side effects that accompany that high, combined with the powerful psychological dependence it creates, makes it an extremely dangerous drug to take. As a very powerful stimulant, cocaine not only gives users more energy, it makes them feel confident and even euphoric, meaning they are extremely elated or happy, usually for no reason. This feeling of elation and power makes users believe they can do anything, yet when this high wears off, they usually feel upset, depressed, tired, and even paranoid. Cocaine has a very interesting history: It has gone from being considered a mild stimulant and then a wonder drug, to a harmless “recreational” drug, and finally to a powerfully addictive and very dangerous illegal drug. Although cocaine has, in fact, been all of these things at one time or another, we know it today to be an addictive drug that can wreck a person physically, mentally, and socially. It can also easily kill people.

Cocaine is extracted from the leaves of the coca shrub (Erythroxylum coca), which grows in the tropical forests on the slopes of the Andes Mountains of Peru. A second species, Erythroxylum novagranatense, grows naturally in the drier mountainous regions of Columbia. For thousands of years, the native populations of those areas chewed the leaves of these plants to help them cope with the difficulty of living at such a high altitude. Chewing raw coca leaves (usually combined with ashes or lime) reduced their fatigue and suppressed their hunger, making them better able to handle the hard work they had to do to live so high up in the mountains. The coca leaves were also used during religious ceremonies and for rituals such as burials. The feelings that the leaves gave to their chewers made them consider the coca plant to be a gift from the gods.

Once European explorers started coming to the Americas in the late fifteenth century, it was only a matter of time until invaders, such as the Spanish, came to the New World seeking riches. By the time the Spanish arrived in what is now Peru, the people of that land, known as the Incas, were already a civilization in decline, and they were easily subdued and conquered. The Spaniards eventually learned that giving coca leaves to native workers enabled them to force the workers to do enormous amounts of work in the gold and silver mines that were located in high altitudes. For the next two hundred years, although some coca plants were taken back to Europe, they were not popular or well-known since they did not travel well and were useless if dried out. Further, the Europeans did not like all the chewing and spitting required to get at the plant’s active ingredient, and until this part of the plant could be isolated, coca leaves were not very much in demand.

All of this changed by the middle of the nineteenth century when German physician Albert Niemann perfected the process of isolating the active part of the drug and improved the process of making it. Niemann extracted a purified form of cocaine from the coca leaves, and wrote about the anesthetic or numbing feeling obtained when he put it on his tongue. Cocaine then began its inevitable introduction into medicine, drink, and finally drug abuse. First it was considered by many doctors to be a wonder drug, and they began prescribing it for all sorts of physical and mental problems. By the 1880s, cocaine was even added to a very popular “medicinal” wine called Vin Mariani. The famous Austrian physician Sigmund Freud, who would become the founder of psychoanalysis, published a paper in 1884 that made many wrong medical claims for cocaine. Although he would later withdraw his claims, Freud did write at the time, “The use of coca in moderation is more likely to promote health than to impair it.”

In 1888, a soft drink named “Coca-Cola” was developed in America that contained cocaine and advertised itself as “the drink that relieves exhaustion.” By 1908, however, the makers of Coca-Cola realized their mistake and removed all the cocaine from it, using only caffeine as a stimulant. By then, the initial enthusiasm for cocaine was seen to be undeserved, and many cases of overuse and dependence eventually forced lawmakers to take action against it. Consequently, in 1914 the United States introduced the Harrison Narcotic Act, which made cocaine illegal. After that, cocaine use was popular only with a fairly small number of artists, musicians, and the very rich, until the 1970s. In that decade, cocaine use skyrocketed as many young people who had earlier smoked marijuana took to cocaine as a drug they believed had no side effects, was safe, and was not addictive.

All of these beliefs were eventually seen to be terribly untrue, as a cocaine epidemic in the 1980s claimed many lives, such as that of comedian John Belushi, and wrecked numerous other lives, such as that of the comedian Richard Pryor. Once it is understood what happens to a person’s nervous system when he or she ingests or takes in cocaine, it is not surprising that the results are often bad and sometimes tragic. The cocaine sold on the streets is usually a white crystalline powder or an off-white chunky material. It is usually diluted with other substances, like sugar, and is introduced into a person’s body by sniffing, swallowing, or injecting it. Most people “snort” the powder or inhale it through their nose, since any of the body’s mucous membranes will absorb it into the bloodstream. Injecting the drug means that it must first be turned into a liquid. Both ways create an immediate effect. Smoking “crack” cocaine delivers a more potent high, since crack is distilled cocaine. In its “rock” form it cannot be snorted, but is smoked in pipes. The name “crack” comes from the crackling sound these rock crystals make when heated and burned.

However the active part of the drug gets into the body, it delivers the same effect to the person’s central nervous system, depending on the amount taken and the user’s past drug experience. Usually within seconds, it travels to the brain and produces a sort of overall anesthetic effect because it interferes with the transmission of information from one nerve cell to another. Since this interference is going on within the reward centers of the brain, the user experiences a fairly short-term high that is extremely pleasurable. Physically, the user’s heart is racing, and his blood pressure, respiration, and body temperature also increase. The user feels temporarily more alert and energetic. The problem is that these feelings do not last very long, and the user must do more cocaine to recapture them.

In tests with experimental animals, cocaine is the only drug that the animals will repeatedly and continuously demand on their own to the point of killing themselves. Although cocaine is not physically addictive the way heroin is (meaning that the user physically craves the drug and suffers withdrawal when off it), it nonetheless creates a profound psychological dependence in which the mind craves the ecstasy that comes with the drug. Further, since the user experiences fatigue and depression when he or she stops, there is little reason to want to quit. Over time, these cravings get stronger and stronger, and the user can only think of how to get another “hit.” This obviously makes them unable to live a normal life without the drug, which has by now taken over their lives.

Severe and heavy overuse can make the abuser suffer dizziness, headache, anxiety, insomnia, depression, hallucinations, and have problems moving about. The increase in blood pressure can cause bleeding in the brain as well as breathing problems, both of which have killed many a user. Often, even physically fit people like Len Bias, the All-American basketball star from the University of Maryland, can suddenly die from ingesting cocaine. The medical risks associated with this drug are great, especially since there is no antidote for an overdose. Taking cocaine also has legal consequences, and besides the disorder and dysfunction it brings to a person’s life, it can also land them in jail. Many American schools also have a zero-tolerance policy, as do many companies and other organizations. Overall, despite the glamour that some people see in the drug, the disadvantages far outweigh the temporary advantages, and rather than improving a person’s life, it can only do the opposite.

 



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Short-term and Long-term Effects of Opiate Addiction

May 6th, 2012
Jamie Staggs asked:


Opiates are often referred to as narcotics and have been used medically to relieve pain for centuries. In the early 19th century, pure morphine extract was suitable for solution, and with the advent of the hypodermic needle in the mid-19th century, injection of morphine became a common method of pain relief. In 1898, heroin was introduced into the medical community as a remedy for addiction to morphine. However, it was soon revealed that heroin was even more likely to produce addiction than morphine. While opiates began their start in the medical community, they have quickly become one of the most commonly abused drug groups. Today, only codeine and morphine are still used in the clinical setting for pain management. The opiates drug group includes opium, morphine, codeine and heroin, among other synthetic opiates such as Demerol.

Short-term and Long-term Effects of Opiates

Opiates can cause serious health complications, such as fatal overdose, spontaneous abortion, and infectious diseases such as HIV/AIDS and hepatitis, particularly in users who inject opiates.

Opiates have short-term effects that appear quite soon after a dose and last a few hours. After injection of opiates, the user typically reports feeling a rush of euphoria, an increase in body temperature, dry mouth, and a heavy feeling in their limbs. The user then spends the next few hours alternating from a wakeful to a drowsy state until the drug wears off.

Regular use of opiates leads to a buildup of a user’s tolerance. This means that the user must increase their subsequent dose of opiates to achieve the same effect as before. As the user increases their dose over time, they develop physical dependency and addiction. Their body has acclimated to the drug use, and has grown to depend on the presence of drugs in order to function properly. If an opiate user stops the intake of that drug, uncomfortable and even dangerous withdrawal symptoms may occur. Death from a opiate overdoese often occurs when a user who has been off opiates for some time resumes taking the same amount of drug they are used to. Because the body’s tolerance has decreased during this time off period, the resulting effect is a drug overdose.

After repeated opiate use over a long peroid of time, long term side effects will begin to appear. Addicts who have been using for a long peroid of time often ignore their health because the only thing that matters is getting more of that drug. This self neglect can take the form of not eating and ignoring personal hygiene, which makes the user more susceptible to disease. Longtime users may develop collapsed veins, infections in their heart and valves, and liver disease. Because opiates depress respiration, pulmonary complications, such as pneumonia, may occur in longtime users due to respiratory depression and the poor health of the drug user.

Opiate Withdrawal

Opiate withdrawal can be incredibly painful, and in some case very dangerous. Withdrawal symptoms may occur as soon as a few hours after the last dose in users who have been regularly abusing opiates. Withdrawal symptoms include intense cravings for opiates, restlessness, body pain, insomnia, diarrhea, vomiting, and cold flashes among other symptoms. In longtime, heavy users who are in poor health, withdrawal can occasionally be fatal. Withdrawal symptoms for most users typically subside within a week.



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The Importance of Preventing Chicken Pox

May 3rd, 2012
Groshan Fabiola asked:




As a disease chicken pox is considered not to be very harmful to a healthy pacient. Recent studies have although showed that it is the leading death bringer compared to measles, mumps, whooping cough and Haemophilus influenzae type B meningitis.

Some 14,000 people are admitted each year into hospitals for chickenpox, 60% of them being children. From 1000 individuals only 5 require hospitalization, and in the worst of cases this disease can prove to be fatal. The type of people witch are at the greatest risk of dying from this disease are actually adults, followed by infants, but from the 100 pacients to die from chickenpox 40 were still children. A vaccine could be used to prevent all of these, however recent studies have shown that the number of pacients is the same in hospitals.

One of the good aspects of the disease is the fact that it actually gives immunity to the body making the chance of getting ill again from this very slim. Aside from itching a few rare complications might appear in pacients.

20% of people who have had chicken-pox might later on in their lives suffer from a reactivation of shingles.

Itching, being the most common complication of the varicella infection, can be easily alleviated with some simple home made remedies.

Secondary Infection and Scarring may also appear; small scars usually remain after the falling of the scabs but this doesn’t last long, the scars clearing up after a few month. In the case of itching there is an all other problem, Staphylococcus aureus or Streptococcus pyogenes bacteria sometimes causing infection in the pacient. Children are the most in danger of this kind of complication because of the simple fact that they are more likely to scratch. Also in children another rare complication would be year infection leading sometimes to hearing loss.

Bacterial Superinfection is the most common serious complication of chickenpox being caused by group A streptococcus. Although mild and not very dangerous its spreading to muscle, fat or even the blood can lead to life threatening situations such as the necrotizing fasciitis (the so-called flesh-eating bacteria) but this is still very rare. Persistent or recurring high fever, redness, pain, and swelling in the skin and in the tissue beneath and even pneumonia are some of the symptoms. In the case of pneumonia the most likely people to suffer complications are pregnant women, smokers, and those with serious medical conditions, serious complications appearing in some cases caused by varicella: lung scaring that makes the pacient’s breathing very difficult.

More complications would even be brain and central nervous system damage or even strokes, but as said they are extremely rare.

For more information about chicken pox vaccine or even about adult chicken pox please review this page http://www.chicken-pox-center.com/



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